作者

Aly

译者

Bersella AI

原文

transfemscience.org/articles/transfem-hormone-guidelines

字数

共 4,407 字，阅读约 22 分钟

关键词

HRT、GAHT、用药指导、临床指南

首次发表于

2020 年 11 月 20 日

最后修订于

2023 年 5 月 23 日

翻译于

2023 年 12 月 30 日

摘要

本文将世界上现行的可提供女性化激素治疗相关信息的临床指南加以汇总。其中包括：世界跨性别健康专业协会（WPATH）发表的《跨性别和多元性别人群健康照护指南》；美国内分泌学会发表的《指南》；美国加州大学旧金山分校（UCSF）跨性别健康专家中心发表的《指南》；等等。

前言

医师会引用临床实践指南（CPG）以学习对不同疾病的照护、并获得相关指引。其中，临床实践指南将特定医学领域的现有科学文献和研究加以回顾和总结；医师毋须考究原始科研文献，便得以安排治疗。尽管文献评述亦有类似作用，但临床实践指南往往更加翔实，且多基于循证医学而立，也会定期进行修订。
制定和维护临床实践指南的有临床医师组织和学会、大学、政府机构，甚至还有大型医院；有的指南是国际/无国界性的，有的则是区域性的。

在跨性别医学方面，已有多份临床实践指南公诸于世（对此加以回顾的有 Deutsch, Radix, & Reisner, 2016; Radix, 2019; Radix, 2019; UpToDate; Bewley et al., 2021; Dahlen et al., 2021; Ziegler, Carroll, & Charnish, 2021）。这些指南涵盖心理治疗、激素治疗、声音治疗和适用于跨性别者的外科手术，等等。跨性别临床实践指南不仅起到教育和指导医师的作用，还可为跨性别者所用，帮助其了解所接受的治疗。

本页收录并维护包含世界上已知的、记载女性化激素治疗相关内容的英语临床指南的一份清单。其中，最主要的指南包括：世界跨性别健康专业协会（WPATH）发表的《跨性别和多元性别人群健康照护指南》（SOC）^{(Coleman et al., 2022)}；美国内分泌学会发表的《指南》^{(Hembree et al., 2017)}；以及美国加州大学旧金山分校（UCSF）发表的《指南》^{(Deutsch, 2016)}。前二者系国际通用，而后者通行于美国。

国际性指南

* 译者注：《SOC 8》已被翻译为中文，详见 PDF 文档或在线网页。
** 译者注：网页版已于 2023 年 10 月 12 日得到更新。

美国地区指南

加拿大地区指南

欧洲地区指南

英国地区指南

* 译者注：该指南原计划于 2018 年修订，附文“2023 年四月注：已计划适时对本文进行修订”“该文件并非完全反映本院现行政策”。
** 译者注：原链接不可达，替换为 Archive.org 存档。

意大利地区指南

澳大利亚地区指南

新西兰地区指南

南非地区指南

其余地区性指南

参考文献

• AusPATH. (2022). Australian Informed Consent Standards of Care for Gender Affirming Hormone Therapy. Australia: Australian Professional Association for Trans Health. [URL] [PDF]
• Bewley, S., Dahlen, S., Connolly, D., Arif, I., Junejo, M., & Catherine, M. (2021). International Clinical Practice Guidelines for Gender Minority/Trans People: Systematic Review & Quality Assessment. How Does the Endocrine Society Fare? Journal of the Endocrine Society, 5(Suppl 1), A791–A791. [DOI:10.1210/jendso/bvab048.1609]
• Bourns, A. (2019). Guidelines for Gender-Affirming Primary Care with Trans and Non-Binary Patients, 4th Edition. Toronto: Rainbow Health Ontario/Sherbourne Health. [URL] [PDF]
• Callen-Lorde Community Health Center. (2018). Protocols for the Provision of Hormone Therapy. New York City: Callen-Lorde Community Health Center. [URL] [PDF]
• Cheung, A. S., Wynne, K., Erasmus, J., Murray, S., & Zajac, J. D. (2019). Position Statement on the Hormonal Management of Adult Transgender and Gender Diverse Individuals. Medical Journal of Australia, 211(3), 127–133. [DOI:10.5694/mja2.50259]
• Coleman, E., Bockting, W., Botzer, M., Cohen-Kettenis, P., DeCuypere, G., Feldman, J., Fraser, L., Green, J., Knudson, G., Meyer, W. J., Monstrey, S., Adler, R. K., Brown, G. R., Devor, A. H., Ehrbar, R., Ettner, R., Eyler, E., Garofalo, R., Karasic, D. H., … & Zucker, K. (2012). [World Professional Association for Transgender Health (WPATH)] Standards of Care for the Health of Transsexual, Transgender, and Gender-Nonconforming People, Version 7. International Journal of Transgenderism, 13(4), 165–232. [DOI:10.1080/15532739.2011.700873] [URL] [PDF]
• Coleman, E., Radix, A. E., Bouman, W. P., Brown, G. R., de Vries, A. L., Deutsch, M. B., Ettner, R., Fraser, L., Goodman, M., Green, J., Hancock, A. B., Johnson, T. W., Karasic, D. H., Knudson, G. A., Leibowitz, S. F., Meyer-Bahlburg, H. F., Monstrey, S. J., Motmans, J., Nahata, L., … & Arcelus, J. (2022). [World Professional Association for Transgender Health (WPATH)] Standards of Care for the Health of Transgender and Gender Diverse People, Version 8. International Journal of Transgender Health, 23(Suppl 1), S1–S259. [DOI:10.1080/26895269.2022.2100644] [URL] [PDF] 译者注：已翻译为中文（在线版 | PDF）
• Cundill, P., Wong, P., Cheung, A., & Brownhill, A. (2020). Hormone Therapy Prescribing Guide for General Practitioners working with Trans, Gender Diverse and Non-Binary Patients [Version 3.0]. Australia: Equinox Gender Diverse Health Centre/Thorne Harbour Health. [URL] [PDF]
• Dahl, M., Feldman, J. L., Goldberg, J., & Jaberi, A. (2015). Endocrine Therapy for Transgender Adults in British Columbia: Suggested Guidelines. Physical Aspects of Transgender Endocrine Therapy. Vancouver: Vancouver Coastal Health. [Google 学术] [PDF]
• Dahlen, S., Connolly, D., Arif, I., Junejo, M. H., Bewley, S., & Meads, C. (2021). International Clinical Practice Guidelines for Gender Minority/Trans People: Systematic Review and Quality Assessment. BMJ Open, 11(4), e048943. [DOI:10.1136/bmjopen-2021-048943]
• Davidson, A., Franicevich, J., Freeman, M., Lin, R., Martinez, L., Monihan, M., Porch, M., Samuel, L., Stukalin, R., Vormohr, J., & Zevin, B. (2013). Protocols for Hormonal Reassignment of Gender. San Francisco: San Francisco Department of Public Health/Tom Waddell Health Center. [Google 学术] [PDF]
• Deutsch, M. B. (Ed.). (2016). Guidelines for the Primary and Gender-Affirming Care of Transgender and Gender Nonbinary People, 2nd Edition. San Francisco: University of California, San Francisco/UCSF Transgender Care. [URL] [PDF]
• Deutsch, M. B., Radix, A., & Reisner, S. (2016). What’s in a Guideline? Developing Collaborative and Sound Research Designs that Substantiate Best Practice Recommendations for Transgender Health Care. AMA Journal of Ethics, 18(11), 1098–1106. [DOI:10.1001/journalofethics.2016.18.11.stas1-1611]
• Feldman, J., & Safer, J. (2009). Hormone Therapy in Adults: Suggested Revisions to the Sixth Version of the Standards of Care. International Journal of Transgenderism, 11(3), 146–182. [DOI:10.1080/15532730903383757]
• Fisher, A. D., Senofonte, G., Cocchetti, C., Guercio, G., Lingiardi, V., Meriggiola, M. C., Mosconi, M., Motta, G., Ristori, J., Speranza, A. M., Pierdominici, M., Maggi, M., Corona, G., & Lombardo, F. (2021). SIGIS–SIAMS–SIE position statement of gender affirming hormonal treatment in transgender and non-binary people. Journal of Endocrinological Investigation, 45(3), 657–673. [DOI:10.1007/s40618-021-01694-2]
• Godano, A., Maggi, M., Jannini, E., Meriggiola, M. C., Ghigo, E., Todarello, O., Lenzi, A., & Manieri, C. (2009). SIAMS-ONIG Consensus on Hormonal Treatment in Gender Identity Disorders. Journal of Endocrinological Investigation, 32(10), 857–864. [DOI:10.1007/BF03345758]
• Gorton, N., Jaffe, J. M., Thompson, J., Menkin, D., Nesteby, A., Dunn, D., Baker, K. K., Harbatkin, D., Do, T., Radix, A., Meacher, P., Goldstein, Z., Carpenter, W., Caine, M., Henn, S., Murayama, R., Feldmann, J., & Zayas, S. (2019). TransLine Gender Affirming Hormone Therapy Prescriber Guidelines. San Francisco: Lyon-Martin Health Services/TransLine. [URL] [PDF]
• Health Policy Project, Asia Pacific Transgender Network, United Nations Development Programme. (2015). Blueprint for the Provision of Comprehensive Care for Trans People and Trans Communities. Washington, DC: Futures Group, Health Policy Project. [PDF]
• Hembree, W. C., Cohen-Kettenis, P., Delemarre-Van De Waal, H. A., Gooren, L. J., Meyer III, W. J., Spack, N. P., Tangpricha, V., & Montori, V. M. (2009). Endocrine treatment of transsexual persons: an Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism, 94(9), 3132–3154. [DOI:10.1210/jc.2009-0345]
• Hembree, W. C., Cohen-Kettenis, P. T., Gooren, L., Hannema, S. E., Meyer, W. J., Murad, M. H., Rosenthal, S. M., Safer, J. D., Tangpricha, V., & T’Sjoen, G. G. (2017). Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons: An Endocrine Society Clinical Practice Guideline. The Journal of Clinical Endocrinology and Metabolism, 102(11), 3869–3903. [DOI:10.1210/jc.2017-01658] [PDF]
• International Planned Parenthood Federation (IPPF). (2015). IMAP Statement on Hormone Therapy for Transgender People. International Medical Advisory Panel/International Planned Parenthood Federation. [URL] [PDF]
• Latkin, S., & Coakley, G. (2017). [Transgender Women] Prescribing Guidelines. Doncaster/Bassetlaw: Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust. [PDF] 译者注：原链接不可达，替换为 Archive.org 存档
• Majumder, A., Chatterjee, S., Maji, D., Roychaudhuri, S., Ghosh, S., Selvan, C., George, B., Kalra, P., Maisnam, I., & Sanyal, D. (2020). IDEA Group Consensus Statement on Medical Management of Adult Gender Incongruent Individuals Seeking Gender Reaffirmation as Female. Indian Journal of Endocrinology and Metabolism, 24(2), 128–135. [DOI:10.4103/ijem.IJEM_593_19]
• Oliphant, J., Veale, J., Macdonald, J., Carroll, R., Johnson, R., Harte, M., Stephenson, C. & Bullock, J. (2018). Guidelines for Gender Affirming Healthcare for Gender Diverse and Transgender Children, Young People and Adults in Aotearoa New Zealand. Waikato: Transgender Health Research Lab/University of Waikato. [URL] [PDF]
• Pan American Health Organization, John Snow, Inc., World Professional Association for Transgender Health, et al. (2014). Blueprint for the Provision of Comprehensive Care for Trans Persons and Their Communities in the Caribbean and Other Anglophone Countries. Arlington: John Snow, Inc. [Alt] [PDF]
• Radix, A. (2019). Hormone Therapy for Transgender Adults. The Urologic Clinics of North America, 46(4), 467–473. [DOI:10.1016/j.ucl.2019.07.001]
• Radix, A. (2019). Primary Care of Transgender Adults. In Poretsky, L., & Hembree, W. C. (Eds.). Transgender Medicine: A Multidisciplinary Approach (Contemporary Endocrinology) (pp. 51–67). Cham: Humana Press. [DOI:10.1007/978-3-030-05683-4_4]
• Sappho for Equality. (2019). A Good Practice Guide to Gender-Affirmative Care. Kolkata: Sappho for Equality. [PDF]
• Seal, L. J. (2016). Information About Hormonal Treatment for Trans Women. London: West London Mental Health NHS Trust/West London NHS Trust. [PDF]
• Seal, L., & Barrett, J. (2017). Shared Care Prescribing Guidance for Treatment of Gender Dysphoria in Transwomen (Male to Female Transsexuals). London: West London Mental Health NHS Trust/West London NHS Trust. [PDF]
• Sullivan, C., & Dean, J. (2015). Prescribing Guideline. Pharmacological Treatment of Gender Dysphoria. Devon: Devon Partnership NHS Trust. [PDF]
• Tangpricha, V., & Safer, J. D. (2020). Transgender Women: Evaluation and Management. UpToDate. [URL] [PDF] 译者注：2023 年 10 月已更新
• Telfer, M. M., Tollit, M. A., Pace, C. C., & Pang, K. C. (2020). Australian Standards of Care and Treatment Guidelines for Trans and Gender Diverse Children and Adolescents Version 1.2. Melbourne: The Royal Children’s Hospital. [PDF]
• Thomas, C. (2015). Guidelines for the Use of Feminising Hormone Therapy. Information for Primary Care. Sunderland: City Hospitals Sunderland NHS Trust. [PDF]
• Thompson, J., Hopwood, R. A., deNormand, S., & Cavanaugh, T. (2021). Medical Care of Trans and Gender Diverse Adults. Boston: Fenway Health. [URL] [PDF]
• Tomson, A., McLachlan, C., Wattrus, C., Adams, K., Addinall, R., Bothma, R., Jankelowitz, L., Kotze, E., Luvuno, Z., Madlala, N., Matyila, S., Padavatan, A., Pillay, M., Rakumakoe, M. D., Tomson-Myburgh, M., Venter, W., & de Vries, E. (2021). Southern African HIV Clinicians’ Society gender-affirming healthcare guideline for South Africa. Southern African Journal of HIV Medicine, 22(1), a1299. [DOI:10.4102/sajhivmed.v22i1.1299] [PDF]
• Trans Care BC. (2021). Gender-affirming Care for Trans, Two-Spirit, and Gender Diverse Patients in BC: A Primary Care Toolkit. Vancouver: Provincial Health Services Authority/Trans Care BC. [URL] [PDF]
• T’Sjoen, G., Arcelus, J., De Vries, A. L., Fisher, A. D., Nieder, T. O., Özer, M., & Motmans, J. (2020). European Society for Sexual Medicine Position Statement “Assessment and Hormonal Management in Adolescent and Adult Trans People, With Attention for Sexual Function and Satisfaction”. The Journal of Sexual Medicine, 17(4), 570–584. [DOI:10.1016/j.jsxm.2020.01.012]
• UpToDate. (2021). Society Guideline Links: Transgender Health. UpToDate. [URL]
• Vacharathit, V., Ratanalert, W., & Samitpol, K. (2021). The Thai Handbook of Transgender Healthcare Services. Thailand: Center of Excellence in Transgender Health/Chulalongkorn University. [URL] [PDF]
• Wilczynski, C., & Emanuele, M. A. (2014). Treating a transgender patient: overview of the guidelines. Postgraduate Medicine, 126(7), 121–128. [DOI:10.3810/pgm.2014.11.2840]
• Wylie, K., Barrett, J., Besser, M., Bouman, W. P., Bridgman, M., Clayton, A., Green, R., Hamilton, M., Hines, M., Ivbijaro, G., Khoosal, D., Lawrence, A., Lenihan, P., Loewenthal, D., Ralph, D., Reed, T., Stevens, J., Terry, T., Thom, B., Thornton, J., Walsh, D., & Ward, D. (2014). Good Practice Guidelines for the Assessment and Treatment of Adults with Gender Dysphoria. Sexual and Relationship Therapy, 29(2), 154–214. [DOI:10.1080/14681994.2014.883353]
• Ziegler, E., Carroll, B., & Charnish, E. (2021). Review and Analysis of International Transgender Adult Primary Care Guidelines. Transgender Health, 6(3), 139–147. [DOI:10.1089/trgh.2020.0043]

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